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生孩子会让你“折寿”吗?英语文章分享

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Women who give birth may be biologically "older" than women who don't, a new study suggests.
一项新研讨发现,生过孩子的女人在生理上会比那些没有生过的“更老”。

For the study, the researchers analyzed information from 1,556 US women ages 20 to 44 who took part in a national survey from 1999 to 2002, which involved giving blood samples.
在该研讨中,研讨人员们剖析了20-44岁之间的1556名美国女人信息,她们参加了1999年至2002年期间的全国查询,并给出了血液样本。

生孩子真的会让你“折寿”吗?

The researchers looked at the genetic material inside the women's cells, specifically the length of their telomeres. These are caps on the ends of chromosomes that protect the chromosomes from damage. Telomeres naturally shorten as people age, but the structures don't shorten at the same rate in every person. The longer a person's telomeres are, the more times their cells could hypothetically still divide, research has shown. Thus, telomeres are considered a marker of biological age — that is, the age of a person's cells, rather than the individual's chronological age.
研讨人员们调查了这些女人细胞内的遗传物质,尤其是她们端粒的长度。这些坐落染色体末端的小帽子可以维护染色体不受损。人们在变老的过程中,端粒也会天然缩短,但这个结构在每个人身上变短的速度均不同。一个人的端粒越长,他们的细胞理论上可以割裂的次数就越多。而且,端粒也被科学家们视为生理年纪的符号,即一个人的细胞年纪,而不是他们的实践年纪。

Women in the survey who said they'd given birth to at least one child had telomeres that were about 4 percent shorter, on average, than those of women who'd never given birth. The findings held even after the researchers took into account other factors that could affect telomere length, including the women's chronological age, body mass index and smoking habits.
在研讨中,至少生过一个孩子的女人端粒长度平均比那些未出产过的女人短百分之四。即使研讨人员们考虑了其它能影响端粒长度的要素(比方她们的实践年纪、身体质量指数和吸烟习气),这些发现照旧站得住脚。

These findings suggest that a "history of live birth may be associated with shorter telomeres," the researchers wrote in their abstract, which was presented at the meeting of the American Public Health Association in Denver.
这些发现标明出产史可能与更短的端粒之间存在着联络。该研讨的概述在美国公共卫生协会于丹佛市举行的会议上发布。

The study was not designed to determine the reason behind the link, the researchers said. But one hypothesis is that having children increases stress levels, and high stress has been linked with shorter telomeres, the scientists said.
该研讨并未探究这一联络背面的原因,但有猜想以为生孩子会增加女人的压力,而高压与更短的端粒有关。

"It is possible that pregnancy, birth and child-rearing can induce chronic stress, leading to shorter telomere length perhaps through an inflammatory pathway," said study researcher Anna Pollack, an assistant professor and environmental and reproductive epidemiologist at George Mason University. However, because the survey was conducted at a single point in time, the researchers cannot determine which came first in the women's lives — giving birth or having shorter telomeres, Pollack said. It's also possible that for some yet-unknown reason, women with shorter telomeres are more likely than women with longer ones to have children, Pollack said.
美国乔治梅森大学的助教、生态环境与生殖流行病学家安娜•波莱克参与了该研讨,她表明:“有可能怀孕、出产和抚育孩子带来了缓慢压力,并经过炎症通路缩短了端粒长度。”但是,由于查询是在某个时刻点开展的,研讨人员们无法断定生孩子与更短的端粒长度之间,哪一个先呈现。波莱克说,有可能出于某些未知的原因,端粒更短的女人比端粒更长的女人更有可能生孩子。

More studies are needed that follow women over time and measure the length of their telomeres before, during and after pregnancy, she said.
她说,还需要进一步的追踪研讨来断定女人的端粒在生孩子之前、怀孕期间和产后的长度。

"It would be interesting to see how telomere length changes during pregnancy, after birth and during the child-rearing years, and how these changes compare to women who do not have children," Pollack said.
波莱克说:“调查端粒长度在孕期、产后和哺育孩子过程中的改变,并将其与没有生过孩子的女人比较是一件非常风趣的工作。”

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